A position of responsibility.

• When the office of Secretary of State is vacant, its duties fall upon an official within the department.
• Do not conflate the officeholder with the office; the distinction sometimes matters.

Official position, particularly high employment within government; tenure in such a position.

• She held office as secretary of state until she left office to run for office.
• Fla.[…]Well, would I were / Gently put out of Office, before I were forc'd out[…]

A duty, particularly owing to one's position or station; a charge, trust, or role; (obsolete, rare) moral duty.

• Ang.... Doe you your office, or giue vp your Place, And you shall well be spar'd.
• The Sun was ſunk, and after him the Starr / Of Heſperus, whoſe Office is to bring / Twilight upon the Earth[…]

archaicFunction: anything typically done by or expected of something.

• In this experiment the several intervals of the teeth of the comb do the office of so many prisms.
• I hope you saw her petticoat, six inches deep in mud,[…]and the gown which had been let down to hide it, not doing its office.

regionalA service, a kindness.

• The secretary prevailed at the negotiations through the good offices of the Freedonian ambassador.
• ...which we have hitherto forborne to graunt... for the evell offices whiche her other Secretary did there.

slangInside information.

• Giving the office—is when you suffer any person, who may stand behind your chair, to look over your hand.
• "[…]What is there for me in it?" "Not a shilling." "What? Wasn't it I that gave the information? Where would you have been if I had not given you the office?"

A room, set of rooms, or building used for non-manual work, particularly

• The office of the Secretary of State is cleaned when it is vacant.
• Now it came to paſſe that at what time the chest was brought vnto the kings office, by the hand of the Leuites[…]

A room, set of rooms, or building used for non-manual work

• The “Pall Mall Gazette” had its offices[…]in Catherine Street[…]

A room, set of rooms, or building used for non-manual work

• There will be some of the family waiting for you at the coach-office.

medicinesciencesA room, set of rooms, or building used for non-manual work

• This one was made out at a private office—Office is American for Surgery.

The staff of such places.

• The whole office was there... well, except you, of course.

The administrative departments housed in such places, particularly

• He's from our public relations office.

The administrative departments housed in such places

• The secretary of state's British colleague heads the Foreign and Commonwealth Office.

The administrative departments housed in such places

• He worked as the receptionist at the Akron office.
• But there is an Insuring-Office set up in the Gospel, as to the venture of our eternities.

datedThe parts of a house or estate devoted to manual work and storage, as the kitchen, scullery, laundry, stables, etc., particularly (euphemistic, dated) a house or estate's facilities for urination and defecation: outhouses or lavatories.

• As for the Offices, let them stand at some Distance from the House, with some low covered Galleries, to pass from them to the Palace it self.
• ... proposals for erecting 500 Publick Offices of Ease in London and Westminster...

obsoleteA piece of land used for hunting; the area of land overseen by a gamekeeper.

• All hunt in James Whitendales office.

obsoleteslangA hangout: a place where one is normally found.

• His Office, any Man's ordinary Haunt, or Plying-place, be it Tavern, Ale-house, Gaming-house.

datedslanggovernmentmilitarypoliticsA plane's cockpit, particularly an observer's cockpit.

• I withdraw into ‘the office’, otherwise the observer's cockpit.
• In the slang of the Royal Air Force man, the cockpit of his plane is the ‘pulpit’ or ‘office’, the glass covering over it the ‘greenhouse’.

computingengineeringmathematicsA collection of business software typically including a word processor and spreadsheet and slideshow programs.

obsoleteAn official or group of officials; (figuratively) a personification of officeholders.

• […]For who would beare... The pangs of despiz'd loue, the lawes delay, The insolence of office... When he himselfe might his quietas make... With a bare bodkin?
• Ped. Now Mr. Office: What is the Reason that your vigilant Greatness And your Wife's wonderful wiseness have lock'd up from me The way to see my Mistress? Who's Dog's dead now, That you observe these Vigils?

obsoleteA bodily function, (particularly) urination and defecation; an act of urination or defecation.

• Cassio.... Whom I, with all the Office of my heart Intirely honour[…]
• Washing themselves, as they doe also after the offices of Nature.

obsoleteThe performance of a duty; an instance of performing a duty.

• […]whan the Quene of riche Arabia sawe all the wyſzdome of Salomon[…]⁊ the offyces of his miniſters, and their garmentes[…]ſhe wondred exceadingly[…]
• At Rome (nor think me partial to the Poor) / All Offices of ours are out of Door[…]