To enervate someone is to make them feel tired and weak — to drain the strength out of them. Heavy heat, a long dull meeting, or a slow illness can enervate you. It is a formal, slightly old word; most people now say wear you out or drain you. Writers and some doctors still use it. There is a rare adjective use, enervate, meaning already weak, but the verb is the one you will meet. Though actually, this is a draining tiredness, not the healthy tiredness after sport. And it is the opposite of energize, even though the two look a little related on the page.

使衰弱；使人疲憊無力（書面、正式）