If someone is meddlesome, they keep stepping into other people's business when nobody asked them to, and it gets on people's nerves. It is not a compliment. A meddlesome neighbour might listen at the door, tell you how to raise your child, or 'fix' a problem that was not theirs. The word points to a habit, not one clumsy moment: a meddlesome person does this again and again. It feels a little old-fashioned and a little sharp; many people now say nosy or interfering instead, but meddlesome is still clear and a bit literary. Though actually, the meddlesome person often believes they are helping. That is why the word stings: the help was never wanted.