The ASPCA is an American charity that looks after animals, especially pets that have been hurt, badly treated, or left with no home. They try to find new families for them, and they speak against cruelty. You say the letters one by one: A-S-P-C-A. Though actually, this is a United States group, not a world government for animals. Britain has the RSPCA; Taiwan has its own groups. In American news, adverts, and TV, ASPCA comes up a lot. It is a proper name, so it stays in capitals.